BDBM50233772 CHEMBL252037::N-[(R)-1-[(3-benzyl-3H-imidazo[4,5-b]pyridin-2-ylmethyl)-carbamoyl]-2-(2-trifluoromethyl-phenyl)-ethyl]-2,2-dimethyl-propionamide

SMILES CC(C)(C)C(=O)N[C@H](Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1Cc1ccccc1

InChI Key InChIKey=WKFPMXWZIKXFBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233772   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50233772(N-[(R)-1-[(3-benzyl-3H-imidazo[4,5-b]pyridin-2-ylm...)
Affinity DataIC50: 261nMAssay Description:Blockade of human Nav1.7 channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50233772(N-[(R)-1-[(3-benzyl-3H-imidazo[4,5-b]pyridin-2-ylm...)
Affinity DataIC50: 1.46E+3nMAssay Description:Blockade of human Nav1.8 channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed