BDBM50234052 CHEMBL4096342::US9765018, Example 224

SMILES Cc1ccccc1NC(=O)Nc1cc(ccc1Oc1ccccc1C(C)(C)C)-c1cccc(c1)C(O)=O

InChI Key InChIKey=JALVGVUQGBFXGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234052   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50234052(US9765018, Example 224 | CHEMBL4096342)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production preincubated with cells followed by IFN-g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50234052(US9765018, Example 224 | CHEMBL4096342)
Affinity DataIC50: 7.50E+3nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
US Patent