BDBM50234572 CHEMBL4086643

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(F)c(c3)C#Cc3cncc4ccccc34)cc2C(F)(F)F)CC1

InChI Key InChIKey=IWAIRGHIYWNQTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234572   

TargetVascular endothelial growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50234572(CHEMBL4086643)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant KDR (unknown origin) using poly (Glu, Tyr) 4:1 after 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50234572(CHEMBL4086643)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 after 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details Article
PubMed