BDBM50234790 (E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde oxime::3-chloro-4-(4-hydroxyphenyl)salicylaldoxime::CHEMBL405154

SMILES Oc1ccc(cc1)-c1ccc(CN=O)c(O)c1Cl

InChI Key InChIKey=CIYDFCOZUPKHFA-UHFFFAOYSA-N

Data  2 KI  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50234790   

TargetEstrogen receptor beta(Human)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50234790((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at full-length human estrogen receptor beta expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50234790((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at full length human ERbeta receptor expressed in human HEC-1 cells assessed as (ERE)2-pS2-luc reporter gene transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50234790((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]estradiol from purified full length human ERbeta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50234790((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at full-length human estrogen receptor alpha expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50234790((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at full-length human estrogen receptor alpha expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50234790((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at full length human ERalpha receptor expressed in human HEC-1 cells assessed as (ERE)2-pS2-luc reporter gene transcriptional activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50234790((E)-2-chloro-3,4'-dihydroxybiphenyl-4-carbaldehyde...)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]estradiol from purified full length human ERalpha receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed