BDBM50234811 CHEMBL4086603

SMILES CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(o2)-c2ccc(CC#N)c(c2)-c2ccccn2)c1

InChI Key InChIKey=ZIKVYDDNZDVYHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234811   

TargetVascular endothelial growth factor receptor 2(Human)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234811(CHEMBL4086603)
Affinity DataIC50: 23nMAssay Description:Inhibition of VEGFR2 (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234811(CHEMBL4086603)
Affinity DataIC50: 80nMAssay Description:Inhibition of human CLK1 using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed