BDBM50235185 CHEMBL4063541

SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cncc(c1)-c1ccc(s1)-c1ccc2CCNC(=O)c2c1

InChI Key InChIKey=YMQJMPPHSFJMIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235185   

TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50235185(CHEMBL4063541)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant perforin (unknown origin) assessed as decrease in lysis of 51Cr-labelled human Jurkat cells by measuring 51Cr release prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50235185(CHEMBL4063541)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Perforin-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed