BDBM50235207 CHEMBL4087753

SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCC2(CN(C2)c2ccc(cn2)C#N)CC1

InChI Key InChIKey=GYCSEJAVIJOJHF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50235207   

LigandPNGBDBM50235207(CHEMBL4087753)
Affinity DataIC50: 104nMAssay Description:Inhibition of human ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
LigandPNGBDBM50235207(CHEMBL4087753)
Affinity DataIC50: 104nMAssay Description:Assay Protocol: The ROMK channel functional thallium flux assay was performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent

LigandPNGBDBM50235207(CHEMBL4087753)
Affinity DataIC50: 1.05E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed