BDBM50235575 CHEMBL253222::N-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-4-yloxy)-3-fluorophenyl)nicotinamide

SMILES CN(C)CCCOc1cn2ncnc(Oc3ccc(NC(=O)c4cccnc4)cc3F)c2c1C

InChI Key InChIKey=LYUZVGOQWISIPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235575   

TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50235575(N-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50235575(N-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed