BDBM50235751 CHEMBL255007::{4-[2-((S)-1-amino-2-methyl-propyl)-4-methyl-phenyl]-piperazin-1-yl}-[(2R,3R)-3-(4-chloro-phenyl)-1-((R)-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-pyrrolidin-2-yl]-methanone

SMILES CC(C)[C@H](N)c1cc(C)ccc1N1CCN(CC1)C(=O)[C@H]1[C@H](CCN1C(=O)[C@H]1Cc2ccccc2CN1)c1ccc(Cl)cc1

InChI Key InChIKey=TWSXEPWFFLQDCT-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235751   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50235751({4-[2-((S)-1-amino-2-methyl-propyl)-4-methyl-pheny...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at MC4 receptor by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50235751({4-[2-((S)-1-amino-2-methyl-propyl)-4-methyl-pheny...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125]NDPMSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed