BDBM50235801 CHEMBL4098455

SMILES CCN(C)C(=O)Oc1cc(OC(=O)N(C)CC)cc(c1)C(O)CNC(C)(C)CC

InChI Key InChIKey=YITYTBZFPWLRCG-UHFFFAOYSA-N

Data  4 IC50  2 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50235801   

TargetCholinesterase(Horse)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235801(CHEMBL4098455)
Affinity DataKoff:  2.48E+3s-1Assay Description:Irreversible inhibition of equine serum BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235801(CHEMBL4098455)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human erythrocytes AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235801(CHEMBL4098455)
Affinity DataKoff:  1.22E+5s-1Assay Description:Irreversible inhibition of human plasma BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235801(CHEMBL4098455)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235801(CHEMBL4098455)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235801(CHEMBL4098455)
Affinity DataIC50: 116nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed