BDBM50236281 CHEMBL4076141

SMILES [H][C@@]12CO[C@@]([H])([C@H](O)[C@@H](O)[C@@H]1O)N2C(=S)NCCCCCCCCCNC(=O)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChI Key

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50236281   

TargetLysosomal acid glucosylceramidase(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  900nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 in presence of bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 in presence of bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 by luminescence sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 by luminescence sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed