BDBM50236366 CHEMBL4083038

SMILES Cn1c(cc2sccc12)C(=O)Nc1cccc(COc2ccc(OC3CCNCC3)cc2)c1

InChI Key InChIKey=NCKQOQVVTYHFPU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50236366   

TargetAmine oxidase [flavin-containing] B(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236366(CHEMBL4083038)
Affinity DataIC50: 7.16E+3nMAssay Description:Inhibition of recombinant human MAOB incubated for 15 mins measured after 30 mins by luminescence-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236366(CHEMBL4083038)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KDM1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236366(CHEMBL4083038)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236366(CHEMBL4083038)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236366(CHEMBL4083038)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAOA incubated for 15 mins measured after 30 mins by luminescence-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed