BDBM50236540 CHEMBL4080994

SMILES Oc1ccc(NC(=O)c2cnc3[nH]cc(-c4ccc(O)cc4)c3c2)cc1

InChI Key InChIKey=BUDHBLBYISRDCR-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50236540   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236540(CHEMBL4080994)
Affinity DataIC50: 128nMAssay Description:Inhibition of DYRK1B (unknown origin) using woodtide as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236540(CHEMBL4080994)
Affinity DataIC50: 344nMAssay Description:Inhibition of DYRK1A (unknown origin) using woodtide as substrate after 10 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236540(CHEMBL4080994)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of DYRK2 (unknown origin) using woodtide as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236540(CHEMBL4080994)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed