BDBM50236545 CHEMBL4087125

SMILES Oc1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccc(cc1)-c1nnn[nH]1

InChI Key InChIKey=XVVPNHZWUXCHJE-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50236545   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236545(CHEMBL4087125)
Affinity DataIC50: 42nMAssay Description:Inhibition of DYRK1B (unknown origin) using woodtide as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236545(CHEMBL4087125)
Affinity DataIC50: 86nMAssay Description:Inhibition of DYRK1A (unknown origin) using woodtide as substrate after 10 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236545(CHEMBL4087125)
Affinity DataIC50: 408nMAssay Description:Inhibition of DYRK2 (unknown origin) using woodtide as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236545(CHEMBL4087125)
Affinity DataEC50:  7.00E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed