BDBM50236995 CHEMBL4078375

SMILES COc1ccc(SCc2cnc(SCc3c(F)cc(cc3F)S(=O)(=O)N(CCC[N+](C)(C)C)CCC[N+](C)(C)C)n2-c2ccc(F)cc2)cc1OC

InChI Key InChIKey=MNBFQEWQWAXVHG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236995   

TargetG-protein coupled bile acid receptor 1(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50236995(CHEMBL4078375)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at TGR5 in STC1 cells derived from double transgenic mouse expressing rat insulin promoters linked to SV40 large T antigen and to po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50236995(CHEMBL4078375)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at TGR5 in human NCI-H716 cells assessed as increase in cAMP level after 40 mins by mass spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed