BDBM50237304 CHEMBL4093325

SMILES CC1(N(CCc2cc(O)ccc12)c1ccc(cc1)C1CC1)c1ccc(\C=C\C(O)=O)cc1

InChI Key InChIKey=PPPWPXYBBQNZFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237304   

TargetEstrogen receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50237304(CHEMBL4093325)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of estrogen-induced transcription preincubated overnight followed by estrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50237304(CHEMBL4093325)
Affinity DataIC50: 0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2019
Entry Details Article
PubMed