BDBM50237503 CHEMBL4093720

SMILES C[C@@]1(CCOc2cc(F)c(cc2F)S(=O)(=O)Nc2ncns2)CC[C@H](N)CC1

InChI Key InChIKey=FKGBDYKCOHLSSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237503   

TargetSodium channel protein type 5 subunit alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50237503(CHEMBL4093720)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human Nav1.5 expressed in HEK293 cells assessed as reduction in peak inward current at -50 mV holding potential measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50237503(CHEMBL4093720)
Affinity DataIC50: 780nMAssay Description:Inhibition of human CYP3A4 assessed as inhibition of dealkylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2019
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50237503(CHEMBL4093720)
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant human Nav1.7 expressed in HEK293 cells assessed as reduction in peak inward current at -60 mV holding potential measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2019
Entry Details Article
PubMed