BDBM50237553 CHEMBL4071058

SMILES CC(C)(C)OC(=O)NCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key InChIKey=JUBMOVBFVJPSAO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50237553   

TargetEpidermal growth factor receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237553(CHEMBL4071058)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of EGFR (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237553(CHEMBL4071058)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Aurora B (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237553(CHEMBL4071058)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of RAF (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237553(CHEMBL4071058)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50237553(CHEMBL4071058)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of c-MET (unknown origin) measured after 40 mins by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed