BDBM50237596 CHEMBL4099423

SMILES CN[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O

InChI Key InChIKey=INYWOSRMSJBVSL-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50237596   

TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50237596(CHEMBL4099423)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50237596(CHEMBL4099423)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates after 180 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50237596(CHEMBL4099423)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates after 180 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50237596(CHEMBL4099423)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates after 180 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details Article
PubMed