BDBM50237599 CHEMBL4066427

SMILES [H][C@@]12CCC(C[C@@H]([C@@H]1C(=O)OC)c1ccc([125I])cc1)N2C

InChI Key InChIKey=SIIICDNNMDMWCI-QZIRHQCUSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237599   

TargetSodium-dependent serotonin transporter(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50237599(CHEMBL4066427)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]mazindol binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50237599(CHEMBL4066427)
Affinity DataKi:  11nMAssay Description:Inhibition of [3H]mazindol binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50237599(CHEMBL4066427)
Affinity DataKi:  70nMAssay Description:Inhibition of [3H]mazindol binding to recombinant human NET expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details Article
PubMed