BDBM50238413 CHEMBL4075167

SMILES O=C(N1CCCCC1)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1

InChI Key InChIKey=VAPHZNNLLMUXPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238413   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238413(CHEMBL4075167)
Affinity DataIC50: 63nMAssay Description:Binding affinity to TNKS1 in human HeLa cell extract after 2 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238413(CHEMBL4075167)
Affinity DataIC50: 501nMAssay Description:Inhibition of TNKS1 (unknown origin) expressed in HEK293 cells co-expressing TCF/LEF luciferase plasmid assessed as reduction in wnt3a ligand-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed