BDBM50238427 CHEMBL4066552

SMILES COCCN(C)C(=O)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1

InChI Key InChIKey=HNICLLKYKSKWPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238427   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238427(CHEMBL4066552)
Affinity DataIC50: 79nMAssay Description:Inhibition of TNKS1 (unknown origin) expressed in HEK293 cells co-expressing TCF/LEF luciferase plasmid assessed as reduction in wnt3a ligand-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238427(CHEMBL4066552)
Affinity DataIC50: 20nMAssay Description:Binding affinity to TNKS1 in human HeLa cell extract after 2 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed