BDBM50239035 CHEMBL4081914

SMILES COc1cc(ccc1O)-c1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=OIUTUDZPVAEFTJ-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50239035   

TargetCytochrome P450 1B1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human liver CYP1B1 expressed in HEK293 cells using 7-ethoxyresorufin as substrate pretreated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 141nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in yeast cells using 7-ethoxyresorufin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of recombinant human liver CYP1A1 expressed in HEK293 cells using 7-ethoxyresorufin as substrate pretreated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human CYP1B1 expressed in yeast microsomal membranes using 7-ethoxyresorufin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in yeast cells using 7-ethoxyresorufin/3-cyano-7-ethoxycoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human CYP1A1 expressed in yeast microsomal membranes using 7-ethoxyresorufin/3-cyano-7-ethoxycoumarin as substrate by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 expressed in yeast microsomal membranes using dibenzylfluorescein as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2D6 expressed in yeast microsomal membranes using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP1A2 expressed in yeast microsomal membranes using 7-ethoxyresorufin/3-cyano-7-ethoxycoumarin/7-ethoxy-methyloxy-3-cyanocoumari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP2C9 expressed in yeast microsomal membranes using 3-cyano-7-ethoxycoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50239035(CHEMBL4081914)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP2C19 expressed in yeast microsomal membranes using 3-cyano-7-ethoxycoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed