BDBM50239208 CHEMBL4074055

SMILES COc1ccc2[nH]cc(\C=C3/C(=O)Nc4ccccc34)c2c1

InChI Key InChIKey=OEJQBEJOXJYPRT-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239208   

TargetHigh affinity nerve growth factor receptor(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50239208(CHEMBL4074055)
Affinity DataIC50: 27nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50239208(CHEMBL4074055)
Affinity DataIC50: 887nMAssay Description:Inhibition of GAL4 fused TrkA (unknown origin) expressed in PC12 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid measured for 18 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50239208(CHEMBL4074055)
Affinity DataIC50: 887nMAssay Description:Inhibition of GAL4 fused TrkA (unknown origin) expressed in PC12 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid measured for 18 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239208(CHEMBL4074055)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed