BDBM50239249 CHEMBL4104000

SMILES CNC(=O)c1c(oc2ccc(cc12)-c1cc(ccc1C)C(=O)NC1(CC1)c1ncccn1)-c1ccc(F)cc1

InChI Key InChIKey=LUIDEMBRIXHMJX-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239249   

TargetCytochrome P450 2C8(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50239249(CHEMBL4104000)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of microsomal CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50239249(CHEMBL4104000)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human ERG by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50239249(CHEMBL4104000)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of microsomal CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50239249(CHEMBL4104000)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed