BDBM50239858 CHEMBL4067006

SMILES COc1cc(NC(=O)NOCCCCCC(=O)NO)c2nc(OC)cc(C)c2c1

InChI Key InChIKey=LQJAALUQLCRUMG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50239858   

TargetHistone deacetylase 1(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed