BDBM50239908 CHEMBL4093533::US10287286, Example 21

SMILES N#Cc1ncc(cn1)-c1cccc2ncnn12

InChI Key InChIKey=QOMVEWRHNWLNQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239908   

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239908(CHEMBL4093533 | US10287286, Example 21)
Affinity DataIC50: 84nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239908(CHEMBL4093533 | US10287286, Example 21)
Affinity DataIC50: 84nMAssay Description:The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2020
Entry Details
US Patent