BDBM50239944 CHEMBL4061613::US9872852, Example 241

SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CN[C@@H](CO)C(C)C

InChI Key InChIKey=MWIRGLMFWXSACP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239944   

TargetProgrammed cell death 1 ligand 1(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50239944(US9872852, Example 241 | CHEMBL4061613)
Affinity DataIC50: 6nMAssay Description:Binding affinity to His-tagged PD-L1 (unknown origin) assessed as reduction in PD-L1/PD1-Ig interaction preincubated with PD-L1 for 15 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50239944(US9872852, Example 241 | CHEMBL4061613)
Affinity DataIC50: 53nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent