BDBM50240223 CHEMBL4090750

SMILES CN(C(=O)c1cccc(c1)-c1cccs1)c1cc(ccc1C)C(=O)Nc1ccc(CN2CCN(C)CC2)c(c1)C(F)(F)F

InChI Key InChIKey=LKRJNGOFZVQOHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240223   

TargetMast/stem cell growth factor receptor Kit(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50240223(CHEMBL4090750)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50240223(CHEMBL4090750)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed