BDBM50241035 1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dicarbamimidamidophenoxy)cyclohexyl]guanidine::CHEMBL205548

SMILES [#7]\[#6](-[#7])=[#7]\[#6@@H]-1-[#6]-[#6@H](\[#7]=[#6](\[#7])-[#7])-[#6@H](-[#6]-[#6@H]1-[#8]-c1ccc(cc1\[#7]=[#6](\[#7])-[#7])\[#7]=[#6](\[#7])-[#7])-[#8]-c1ccc(cc1\[#7]=[#6](\[#7])-[#7])\[#7]=[#6](\[#7])-[#7]

InChI Key InChIKey=IBSUYPLJVWDCOT-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50241035   

TargetGenome polyprotein(Dengue virus 2)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of dengue virus-2 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus 2)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of dengue virus-4 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus 2)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of dengue virus-3 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus 2)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of dengue virus-1 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Australian National University Canberra

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease expressed in Escherichia coli using Phe-Ala-Ser-Gly-Lys-Arg-pNA assessed as proteolytic cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetFurin(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataKi:  169nMAssay Description:Inhibition of human recombinant furin-dependent anthrax protective antigen processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFurin(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataKi:  169nMAssay Description:Inhibition of Recombinant vaccinia-expressed furin (unknown origin) using Pyr-RTKR-MCA as substrate and measured by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed