BDBM50241096 (S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxamido)-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)piperazine-1-carboxamide::CHEMBL437728

SMILES CN([C@H]1CCc2cc(CN3CCN(CC3)C(N)=O)ccc2C1)C(=O)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=BOZHYJXZRTYKQA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50241096   

TargetMelanin-concentrating hormone receptor 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241096((S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxam...)
Affinity DataKi:  129nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241096((S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxam...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241096((S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxam...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed