BDBM50241269 8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imidazo[1,2-a]pyridine-6-carboxamide::8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide::CHEMBL238146

SMILES CCc1cccc(C)c1CNc1cc(cn2c(C)c(C)nc12)C(N)=O

InChI Key InChIKey=IDSZXCFCCNVXER-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50241269   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241269(8-(2-ethyl-6-methylbenzylamino)-2,3-dimethylH-imid...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed