BDBM50242600 4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-methyl)-N-cyclohexylpiperazine-1-carboxamide::CHEMBL488614

SMILES FC(F)(F)c1ccccc1C(N1CCN(CC1)C(=O)NC1CCCCC1)c1ccc(Cl)cc1

InChI Key InChIKey=NHYLIJVMJKZCQG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50242600   

TargetCannabinoid receptor 1(Human)
Central Research Institute

Curated by ChEMBL
LigandPNGBDBM50242600(4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-met...)
Affinity DataIC50: 186nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHOK1 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Central Research Institute

Curated by ChEMBL
LigandPNGBDBM50242600(4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Central Research Institute

Curated by ChEMBL
LigandPNGBDBM50242600(4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-met...)
Affinity DataIC50: 163nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebella membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed