BDBM50242910 1-[4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl]-3-m-tolylurea::CHEMBL472302

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cnc3ccnn3c2N)c1

InChI Key InChIKey=QQKMHMVISILPIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242910   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50242910(1-[4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl]...)
Affinity DataIC50: 47nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50242910(1-[4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl]...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed