BDBM50243017 1-{2-Piperazin-1-yl-1-[3-(trifluoromethyl)phenyl]ethyl}cyclohexanol Dihydrochloride::CHEMBL470082

SMILES OC1(CCCCC1)C(CN1CCNCC1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=RPFZUEYSRQOPDL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243017   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243017(1-{2-Piperazin-1-yl-1-[3-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243017(1-{2-Piperazin-1-yl-1-[3-(trifluoromethyl)phenyl]e...)
Affinity DataIC50: 94nMAssay Description:Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed