BDBM50243285 2-(4-(2-phenyl-3-(4-((4-(5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)pyrido[3,2-b]pyrazin-6-yl)piperazin-1-yl)ethanol::CHEMBL449989

SMILES OCCN1CCN(CC1)c1ccc2nc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2nnc([nH]2)-c2ccccn2)cc1

InChI Key InChIKey=SQYAUXNWQOZSIY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243285   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243285(2-(4-(2-phenyl-3-(4-((4-(5-(pyridin-2-yl)-4H-1,2,4...)
Affinity DataIC50: 13nMAssay Description:Inhibition of Akt1 by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243285(2-(4-(2-phenyl-3-(4-((4-(5-(pyridin-2-yl)-4H-1,2,4...)
Affinity DataIC50: 48nMAssay Description:Inhibition of Akt2 by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243285(2-(4-(2-phenyl-3-(4-((4-(5-(pyridin-2-yl)-4H-1,2,4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG in embryonic kidney cells by radioligand-binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed