BDBM50243346 CHEMBL510305::rac, syn-5-(cyclohex-2-en-1-yl)-7,9-difluoro-2,2,4-trimethyl 2,5-dihydro-(1H)6-oxa-1-azachrysen

SMILES CC1=CC(C)(C)Nc2ccc3-c4cc(F)cc(F)c4O[C@@H]([C@H]4CCCC=C4)c3c12

InChI Key InChIKey=NMWDBIDJPRRXIY-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243346   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243346(rac, syn-5-(cyclohex-2-en-1-yl)-7,9-difluoro-2,2,4...)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243346(rac, syn-5-(cyclohex-2-en-1-yl)-7,9-difluoro-2,2,4...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243346(rac, syn-5-(cyclohex-2-en-1-yl)-7,9-difluoro-2,2,4...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed