BDBM50243362 7-Amino-6-[4-(3-m-tolylureido)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylic Acid Ethyl Ester::CHEMBL507533

SMILES CCOC(=O)c1cnn2c(N)c(cnc12)-c1ccc(NC(=O)Nc2cccc(C)c2)cc1

InChI Key InChIKey=GWZXHHYGWCEZQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243362   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50243362(7-Amino-6-[4-(3-m-tolylureido)phenyl]pyrazolo[1,5-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50243362(7-Amino-6-[4-(3-m-tolylureido)phenyl]pyrazolo[1,5-...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed