BDBM50243464 (-)-1-[(1R)-1-(3-Chlorophenyl)-2-(dimethylamino)ethyl]cyclohexanol::CHEMBL461095

SMILES CN(C)C[C@@H](c1cccc(Cl)c1)C1(O)CCCCC1

InChI Key InChIKey=ZUFCXVFSSJFSOT-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243464   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243464((-)-1-[(1R)-1-(3-Chlorophenyl)-2-(dimethylamino)et...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243464((-)-1-[(1R)-1-(3-Chlorophenyl)-2-(dimethylamino)et...)
Affinity DataIC50: 46nMAssay Description:Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243464((-)-1-[(1R)-1-(3-Chlorophenyl)-2-(dimethylamino)et...)
Affinity DataIC50: 405nMAssay Description:Inhibition of 5HT uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed