BDBM50243469 (+)-1-[(1R)-1-(3-Chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride::CHEMBL459852

SMILES CN1CCN(C[C@@H](c2cccc(Cl)c2)C2(O)CCCCC2)CC1

InChI Key InChIKey=GRUIIAQNNWQJPW-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243469   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243469((+)-1-[(1R)-1-(3-Chlorophenyl)-2-(4-methylpiperazi...)
Affinity DataKi:  187nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243469((+)-1-[(1R)-1-(3-Chlorophenyl)-2-(4-methylpiperazi...)
Affinity DataKi:  235nMAssay Description:Displacement of [3H]WIN-35428 from human recombinant dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243469((+)-1-[(1R)-1-(3-Chlorophenyl)-2-(4-methylpiperazi...)
Affinity DataIC50: 577nMAssay Description:Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed