BDBM50243720 (R)-N-((S)-3-(2-methoxyphenylthio)-2-methylpropyl)-3,4-dihydro-2H-benzo[b][1,4]oxathiepin-3-amine::3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-methylpropyl]-2H-(3R)-1,5-benzoxathiepin-3-amine::CHEMBL511058

SMILES COc1ccccc1SC[C@@H](C)CN[C@@H]1COc2ccccc2SC1

InChI Key InChIKey=HZQHAAFWVRDHMZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243720   

TargetSodium channel protein type 5 subunit alpha(Human)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50243720(3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-me...)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of sodium Nav1.5 channel assessed as inhibition of late sodium current elicited at -30 mV from holding potential of -110 mVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50243720(3,4-dihydro-N-[(2S)-3-[(2-methoxyphenyl)thio]-2-me...)
Affinity DataIC50: 5.77E+3nMAssay Description:Inhibition of sodium Nav1.5 channel assessed as inhibition of late sodium current elicited at -30 mV from holding potential of -90 mVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed