BDBM50243848 1-(2-Benzenesulfonamido)-2-[5-(N-hydroxypyridin-2(1H)-one)]acetylene::2-((1-hydroxy-6-oxo-1,6-dihydropyridin-3-yl)ethynyl)benzenesulfonamide::CHEMBL486432

SMILES NS(=O)(=O)c1ccccc1C#Cc1ccc(=O)n(O)c1

InChI Key InChIKey=UTFCRDZLUGEEFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243848   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50243848(2-((1-hydroxy-6-oxo-1,6-dihydropyridin-3-yl)ethyny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of lipoxygenase-5 in human ED273b-BT cells assessed as amount of cysteinyl leukotriene secreted after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed