BDBM50243929 4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL488645

SMILES COc1cc(cc(OC)c1OC)C1=C(CNC1=O)c1cn(COC(C)C)c2ccccc12

InChI Key InChIKey=CPWSAJBBZKPYRF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50243929   

TargetVascular endothelial growth factor receptor 3(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human recombinant Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human recombinant SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243929(4-[1-(Isopropoxymethyl)-1H-indol-3-yl]-3-(3,4,5-tr...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed