BDBM50244177 1'-[(3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-3H-spiro[2-benzofuran-1,4'-piperidine]::CHEMBL460893

SMILES Cc1nn(cc1CN1CCC2(CC1)OCc1ccccc21)-c1ccccc1

InChI Key InChIKey=NIHOPCQBRMVPHG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244177   

TargetMu-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244177(1'-[(3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-3H-...)
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244177(1'-[(3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-3H-...)
Affinity DataIC50: 9.70E+3nMAssay Description:Displacement of [3H]U69593 from human cloned kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244177(1'-[(3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-3H-...)
Affinity DataIC50: 740nMAssay Description:Displacement of [35S]MK499 from human ERG in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed