BDBM50244452 (4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-tetrahydrofuran-2-yl)methyl 4-methoxybenzoate::CHEMBL488668::rac-(E)-{2-(Hydroxymethyl)-4-[(4-nitrophenyl)methylene]-5-oxo-2-2,3-dihydrofuryl}methyl 4-Methoxybenzoate::rac-(E/Z)-(4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-tetrahydrofuran-2-yl)methyl 4-methoxybenzoate

SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1

InChI Key InChIKey=COBJXRZGVAGZLH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50244452   

TargetRas guanyl-releasing protein 3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244452(rac-(E/Z)-(4-(4-nitrobenzylidene)-2-(hydroxymethyl...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]PDBu from RasGRP3 expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Mouse)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244452(rac-(E/Z)-(4-(4-nitrobenzylidene)-2-(hydroxymethyl...)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Mouse)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244452(rac-(E/Z)-(4-(4-nitrobenzylidene)-2-(hydroxymethyl...)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244452(rac-(E/Z)-(4-(4-nitrobenzylidene)-2-(hydroxymethyl...)
Affinity DataKi:  136nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed