BDBM50244496 CHEMBL4095248

SMILES C[C@H]1CN(CCN1c1ccc(Nc2cc(nn(C)c2=O)-c2ccnc(N3CCn4c5CC(C)(C)Cc5cc4C3=O)c2CO)nc1)C1COC1

InChI Key InChIKey=GAWFVJJKCKNYLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244496   

TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50244496(CHEMBL4095248)
Affinity DataIC50: 16nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed