BDBM50244525 9-(2-chlorostyryl)-N-(4-(dimethylphosphoryl)phenyl)-9H-purin-6-amine::CHEMBL510891

SMILES CP(C)(=O)c1ccc(Nc2ncnc3n(\C=C\c4ccccc4Cl)cnc23)cc1

InChI Key InChIKey=MZVPLRQASMAJIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244525   

TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50244525(9-(2-chlorostyryl)-N-(4-(dimethylphosphoryl)phenyl...)
Affinity DataIC50: 69nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50244525(9-(2-chlorostyryl)-N-(4-(dimethylphosphoryl)phenyl...)
Affinity DataIC50: 126nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed