BDBM50244557 (R)-2-(3-((3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid::CHEMBL452299

SMILES COc1ccc(cc1)C(=O)c1c(C)n(Cc2cccc(O[C@H](C)C(O)=O)c2)c2ncccc12

InChI Key InChIKey=OMBSMQLLFJMMRZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244557   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244557((R)-2-(3-((3-(4-methoxybenzoyl)-2-methyl-1H-pyrrol...)
Affinity DataEC50:  2.93E+3nMAssay Description:Agonist activity at human PPARgamma receptor expressed in african green monkey COS cells after 48 hrs by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244557((R)-2-(3-((3-(4-methoxybenzoyl)-2-methyl-1H-pyrrol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244557((R)-2-(3-((3-(4-methoxybenzoyl)-2-methyl-1H-pyrrol...)
Affinity DataIC50: 726nMAssay Description:Displacement of [3H]2AD-5075 from GST-tagged human PPARgamma receptor expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed