BDBM50244574 2-hydroxy-5-(4-(3-(trifluoromethyl)phenyl)thiazol-2-ylamino)benzoic acid::CHEMBL452052

SMILES OC(=O)c1cc(Nc2nc(cs2)-c2cccc(c2)C(F)(F)F)ccc1O

InChI Key InChIKey=BILPJSPJEMITCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244574   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50244574(2-hydroxy-5-(4-(3-(trifluoromethyl)phenyl)thiazol-...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human wild type CFTR expressed in rat FRT cells assessed as chloride current by short-circuit current measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed