BDBM50245030 4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyrimidin-4-yl)piperazine-1-carboxamide::CHEMBL508120

SMILES O=C(Nc1ccncn1)N1CCN(CC1)c1nc(ns1)-c1ccccc1

InChI Key InChIKey=GELGBGXOTGHLQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245030   

TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50245030(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyrimidin-4-...)
Affinity DataIC50: 10.3nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50245030(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyrimidin-4-...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed